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So, really, it comes down to Zofran being basically safe, though more research is still being done First trimester exposure to ondansetron was associated with increased risk of cardiac (OR: 1. So, really, it comes down to Zofran being basically safe, though more research is still being done First trimester exposure to ondansetron was associated with increased risk of cardiac (OR: 1. Having charged my memory with the phrase (as to my understanding I hastened with all possible expedition to my Jansenist friend and accosted him with: Tell me if you admit the proximate power. Having charged my memory with the phrase (as to my understanding I hastened with all possible expedition to my Jansenist friend and accosted him with: Tell me if you admit the proximate power. 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A new study from Brigham and Women’s Hospital finds that pregnant women taking the common anti-nausea medication ondansetron during the first trimester have no increased risk of cardiac malformations and only a slight increased risk of oral clefts. A new study from Brigham and Women’s Hospital finds that pregnant women taking the common anti-nausea medication ondansetron during the first trimester have no increased risk of cardiac malformations and only a slight increased risk of oral clefts. Any chemical aka medicine you decide to ingest and subject your child to will intake it as well Indeed, when first trimester ondansetron use has been studied relative to individual birth defects, an increased risk of cardiac malformations, specifically ventricular septal defects (VSD), was reported. Any chemical aka medicine you decide to ingest and subject your child to will intake it as well Indeed, when first trimester ondansetron use has been studied relative to individual birth defects, an increased risk of cardiac malformations, specifically ventricular septal defects (VSD), was reported. Even though some studies indicate that ondansetron is safe to use during the first trimester when most women experience morning sickness. Even though some studies indicate that ondansetron is safe to use during the first trimester when most women experience morning sickness. Flunisolide: (Moderate) Concomitant use of systemic sodium chloride and corticosteroids may result in sodium and fluid retention. Flunisolide: (Moderate) Concomitant use of systemic sodium chloride and corticosteroids may result in sodium and fluid retention. Toward resolution of cardiovascular fully-being disparities in African Americans: design and methods of the Jackson Heart Study. 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